2024 |
Achyranthis radix extract enhances antioxidant effect of pla-centa-derived mesenchymal stem cell on injured human ocular cells |
2024 |
Polystyrene Nanoplastics-Induced Intestinal Barrier Disruption via Inflammation and Apoptosis in Zebrafish Larvae (Danio rerio) |
2024 |
Efficacy and safety of USL for dry eye disease: protocol for a randomized, double-blind, placebo-controlled, parallel, phase 2 clinical trial |
2023 |
Gene expression profiling of nasal inflammatory dysfunctions induced by diesel particles using an in vivo system |
2023 |
Isobavachin from Psoralea corylifolia alleviates lipopolysaccharide-induced inflammatory responses in macrophages and zebrafish by suppressing the MAPK and NF-κB signaling pathways |
2022 |
Particulate matter exposure and the changes in immune bi-omarkers: Effects of Biyeom-go on the nasal mucosa of patients with allergic rhinitis and a particulate matter-treated mouse model |
2021 |
Evaluation of oral toxicity and genotoxicity of Achyranthis Radix extract |
2021 |
Extract of Moutan radicis cortex and Cinnamomi ramulus ameliorates laser-induced choroidal neovascularization in Brown-Norway rats |
2021 |
Damage to Olfactory Organs of Adult Zebrafish Induced by Diesel Particulate Matter |
2020 |
Achyranthis Radix extract loaded eye drop formulation development and novel evaluation method for dry eye treatment |
2020 |
Method for the Rapid Screening of Drug Candidates Using Single‐Protein Tracking in a Living Cell |
2020 |
Anti-angiogenic effect of EGHB010, a standardized herbal formula of Paeoniae radix and Glycyrrhizae radix |
2020 |
The herbal combination CPA4-1 inhibits changes in retinal capillaries and reduction of retinal occludin in db/db mice |
2020 |
Toxicological effects of urban particulate matter on corneal and conjunctival epithelial cells |
2020 |
New application for assessment of dry eye syndrome induced by particulate matter exposure |
2020 |
Anti-inflammatory isocoumarins from the bark of Fraxinus chinensis subsp. rhynchophylla |
2020 |
POCU1b, the n-Butanol Soluble Fraction of Polygoni Cuspidati Rhizoma et Radix, Attenuates Obesity, Non-Alcoholic Fatty Liver and Insulin Resistance via Inhibitions of Pancreatic Lipase and cAMP-dependent PDE activity, AMPK activation and SOCS-3 suppression |
2019 |
Achyranthis radix Extract Improves Urban Particulate Matter-Induced Dry Eye Disease |
2019 |
Polydatin inhibits NLRP3 inflammasome in dry eye disease by attenuating oxidative stress and inhibiting the NF-κB pathway |
2019 |
Topical Application of Liriope platyphylla Extract Attenuates Dry Eye Syndrome Induced by Particulate Matter |
2019 |
Apricot Kernel Extract and Amygdalin Inhibit Urban Particulate Matter-Induced Keratoconjunctivitis Sicca |
2019 |
Polygonum cuspidatum stem extract (PSE) attenuates dry eye disease by inhibiting inflammation and apoptosis |
2019 |
Improvement in diabetic retinopathy through protection against retinal apoptosis in spontaneously diabetic Torii rats mediated by ethanol extract of Osteomeles schwerinae C.K. Schneid. |
2019 |
Pueraria lobata extract protects hydrogen peroxide-induced human retinal pigment epithelial cells death and membrane permeability |
2018 |
Aster Koraiensis extract and chlorogenic acid inhibit retinal angiogenesis in a mouse model of oxygen-induced retinopathy |
2018 |
Identification and Quantification of Human Neutrophil Elastase Inhibitory Caffeoylquinic Acids in the Leaves of Aster koraiensis |
2018 |
홍삼가수분해추출물의 db/db 마우스에서 신장 손상 예방효과 |
2018 |
Aster koraiensis extract improves impaired skin wound healing during hyperglycemia |
2018 |
Aster koraiensis extract lowers postprandial glucose in normoglycemic and high-fat-diet-induced obese mice |
2018 |
The protective effect of Polygonum cuspidatum (PCE) aqueous extract in a dry eye |
2018 |
Antioxidant and α-Glucosidase Inhibitory Activities of the Extracts of Aster koraiensis Leaves |
2018 |
Osteomeles schwerinae extract prevents diabetes-induced renal injury in Spontaneously Diabetic Torii rats |
2017 |
Pectin lyase-modified red ginseng extract exhibits potent anti-glycation effects in vitro and in vivo |
2017 |
GS-E3D, a new pectin lyase-modified red ginseng extract, inhibited diabetes-related renal dysfunction in streptozotocin-induced diabetic rats |
2017 |
EGHB010, a Standardized Extract of Paeoniae Radix and Glycyrrhizae Radix, Inhibits VEGF-Induced Tube Formation In Vitro and Retinal Vascular Leakage and Choroidal Neovascularization In Vivo |
2017 |
Aster koraiensis extract prevents diabetes-induced retinal vascular dysfunction in spontaneously diabetic Torii rats |
2017 |
Phenolic Compounds from the Leaves of Homonoia riparia and their Inhibitory Effects on Advanced Glycation End Product Formation |
2017 |
The role of glycation in the pathogenesis of aging and its prevention through herbal products and physical exercise |
2016 |
Cnidium officinale extract and butylidenephthalide inhibits retinal neovascularization in vitro and in vivo |
2016 |
Topical Application of Apricot Kernel Extract Improves Dry Eye Symptoms in a Unilateral Exorbital Lacrimal Gland Excision Mouse |
2016 |
Esculetin, a Coumarin Derivative, Inhibits Aldose Reductase Activity in vitro and Cataractogenesis in Galactose-Fed Rats. |
2016 |
Jakyakgamcho-tang and its major component, Paeonia lactiflora, exhibit potent anti-glycation properties |
2016 |
Extract of Polygonum cuspidatum Attenuates Diabetic Retinopathy by Inhibiting the High-Mobility Group Box-1 (HMGB1) Signaling Pathway in Streptozotocin-Induced Diabetic Rats. |
2016 |
벌개미취 에탄올추출물의 STZ-유도 당뇨 모델에서의 최종당화산물의 생성 및 교차결합에 미치는 효과 |
2016 |
The Extract of Aster Koraiensis Prevents Retinal Pericyte Apoptosis in Diabetic Rats and Its Active Compound, Chlorogenic Acid Inhibits AGE Formation and AGE/RAGE Interaction |
2016 |
Cytoplasmic translocation of high-mobility group box-1 protein is induced by diabetes and high glucose in retinal pericytes |
2015 |
Inhibitory effect of Samul-tang on retinal neovascularization in oxygen-induced retinopathy |
2015 |
Litsea japonica Extract Inhibits Aldose Reductase Activity and Hyperglycemia-Induced Lenticular Sorbitol Accumulation in db/db Mice. |
2015 |
OSSC1E-K19, a novel phytochemical component of Osteomeles schwerinae, prevents glycated albumin-induced retinal vascular injury in rats. |
2015 |
Epicatechin breaks preformed glycated serum albumin and reverses the retina laccumulation ofadvanced glycation end products |
2015 |
Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin‑induced diabetic rats and its active compound emodin inhibits methylglyoxal‑mediated glycation of proteins |
2015 |
Litsea japonica extract inhibits neuronal apoptosis and the accumulation of advanced glycation end products in the diabetic mouse retina |
2015 |
Effect of Guibi-Tang, a Traditional Herbal Formula, on Retinal Neovascularization in a Mouse Model of Proliferative Retinopathy |
2015 |
Myricetin inhibits advanced glycation end product (AGE)-induced migration of retinal pericytes through phosphorylation of ERK1/2, FAK-1, and paxillin in vitro and in vivo |
2015 |
Vaccinium myrtillus extract prevents or delays the onset of diabetes–induced blood–retinal barrier breakdown |
2015 |
Treadmill Exercise Attenuates Retinal Oxidative Stress in Naturally-Aged Mice: An Immunohistochemical Study |
2015 |
Anti-glycation and anti-angiogenic activities of 5'-methoxybiphenyl-3,4,3'-triol, a novel phytochemical component of Osteomeles schwerinae |
2015 |
Gemigliptin, a dipeptidyl peptidase-4 inhibitor, inhibits retinal pericyte injury in db/db mice and retinal neovascularization in mice with ischemic retinopathy. |
2014 |
Aminoguanidine Protects against Apoptosis of Retinal Ganglion Cells in Zucker Diabetic Fatty Rats |
2014 |
A high-fat diet increases oxidative renal injury and protein glycation in D-galactose-induced aging rats and its prevention by Korea red ginseng |
2014 |
Expression of heat shock protein 90 in the kidneys of diabetic db/db mice |
2014 |
Sipjeondaebo-tang inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy |
2014 |
Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats |
2014 |
HL-217, a new topical anti-angiogenic agent, inhibits retinal vascular leakage and pathogenic subretinal neovascularization in Vldlr−/− mice |
2014 |
Extract of Cassiae semen attenuates diabetic nephropathy via inhibition of advanced glycation end products accumulation in streptozotocin-induced diabetic rats |
2013 |
Effect of KIOM-79 on diabetes-induced myocardial fibrosis in Zucker Diabetic Fatty Rats. |
2013 |
Extract of Litsea japonica ameliorates blood-retinal barrier breakdown in db/db mice. |
2013 |
Ethyl Pyruvate Prevents Methyglyoxal-Induced Retinal Vascular Injury in Rats |
2013 |
Effect of regular exercise on the histochemical changes of ᴅ-galactose-induced oxidative renal injury in high-fat diet-fed rats |
2013 |
The Extract of Litsea japonica Reduced the Development of Diabetic Nephropathy via the Inhibition of Advanced Glycation End Products Accumulation in db/db Mice |
2013 |
Ethyl pyruvate inhibits retinal pathogenic neovascularization by downregulating HMGB-1 expression |
2013 |
Scopoletin Inhibits Rat Aldose Reductase Activity and Cataractogenesis in Galactose-Fed Rats |
2012 |
Renal Podocyte Injury in a RatModel of Type 2 Diabetes Is Prevented byMetformin |
2012 |
Methylglyoxal induces hyperpermeability of the blood-retinal barrier via the loss of tight junction proteins and the activation of matrix metalloproteinases. |
2012 |
Inhibitory Activities of Cudrania tricuspidata Leaves on Pancreatic Lipase in vitro and Lipolysis in vivo |
2012 |
Cycloartane-Type Triterpenes from the Leaves of Homonoia riparia with VEGF-Induced Angiogenesis Inhibitory Activity |
2012 |
Puerarin inhibits the retinal pericyte apoptosis induced by advanced glycation end products in vitro and in vivo by inhibiting NADPH oxidase-related oxidative stress. |
2012 |
KIOM-79 Protects AGE-Induced Retinal Pericyte Apoptosis via Inhibition of NF-kappaB Activation In Vitro and In Vivo |
2011 |
Chlorogenic acid inhibits the formation of advanced glycation end products and associated protein cross-linking. |
2011 |
Combination of Medicinal Herbs KIOM-79 Reduces Advanced Glycation End Product Accumulation and the Expression of Inflammatory Fzceors in the Aorta of Zucker Diabetic Fatty Rats |
2011 |
Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo. |
2011 |
The role of high-mobility group box-1 protein in the development of diabetic nephropathy |
2011 |
Inhibitory Effects of Chlorogenic Acid on Aldose Reductase Activity In Vitro and Cataractogenesis in Galactose-fed Rats |
2011 |
KIOM-79 inhibits aldose reductase acrivity and cataractogenesis in Zucker diabetic fatty rats |
2011 |
Elevated N(epsilon)-(carboxymethyl)lysine are associated with apoptosis of retinal pericytes in streptozotocin-induced diabetic rats |
2011 |
Betulinic Acid has an Inhibitory Effect on Pancreatic Lipase and Induces Adipocyte Lipolysis |
2010 |
Cytotoxic role of methylglyoxal in rat retinal pericytes: Involvement of a nuclear factor-kappaB and inducible nitric oxide synthase pathway. |
2010 |
Protection against advanced glycation end products and oxidative stress during the development of diabetic keratopathy by KIOM-79 |
2010 |
KIOM-79 prevents methyglyoxal-induced retinal pericyte apoptosis in vitro and in vivo. |
2010 |
Involvement of advanced glycation end products, oxidative stress and nuclear factor-kappaB in the development of diabetic keratopathy. |
2010 |
Lens epithelial cell apoptosis initiates diabetic cataractogenesis in the Zucker diabetic fatty rat. |
2010 |
Anti-lipase and Lipolytic Activities of EtOH Extract from Juniperus rigida |
2010 |
KIOM-79 Prevents Lens Epithelial Cell Apoptosis and Lens Opacification in Zucker Diabetic Fatty Rats. |
2010 |
Renal Podocyte Apoptosis in Zucker Diabetic Fatty Rats: Involvement of Methylglyoxal-Induced Oxidative DNA Damage. |
2009 |
알도즈 환원효소 활성억제와 소비톨 축적 억제로 인한 벌개미취 추출물의 당뇨병성 백내장 발병 지연 효능 |
2009 |
Novel application of surface plasmon resonance biosensor chips for measurementof advanced glycation end products in serum of Zucker diabetic fatty rats. |
2009 |
KIOM-79, an Inhibitor of AGEs–Protein Cross-linking, Prevents Progression of Nephropathy in Zucker Diabetic Fatty Rats |
2009 |
Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells |
2009 |
3,5-Di-O-caffeoyl-epi-quinic Acid from the Leaves and Stems of Erigeron annuus Inhibits Protein Glycation, Aldose Reductase, and Cataractogenesis. |
2009 |
Extract of the aerial parts of Aster koraiensis reduced development of diabetic nephropathy via anti-apoptosis of podocytes in streptozotocin-induced diabetic rats. |
2008 |
산수유씨의 최종당화산물의 형성 및 교차결합에 미치는 효과 |
2008 |
스트렙토조토신으로 유도된 당뇨백서의 망막과 혈청에서 혈관내피세포 성장인자와 최종당화산물의 과발현 및 수정체 혼탁 |
2008 |
KIOM-79 prevents apoptotic cell death and AGEs accumulation in retinas of diabetic db/db mice |
2008 |
Flavan-3-ols from Ulmus davidiana var. japonica with Inhibitory Activity on Protein Glycation |
2007 |
Effects of KIOM-79 on hyperglycemia and diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats |
2007 |
Effects of magnolol (5,5'-diallyl-'2,2'-dihydroxybiphenyl) on diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats |
2007 |
Anthraquinones from the seeds of Cassia tora with inhibitory activity on protein glycation and aldose reductase |
2006 |
복합한약제제 KIOM-79의 STZ 유도 당뇨 모델에서의 최종당화산물 생성 및 Type IV Collagen 및 TGF-β1의 발현억제 효과 |
2006 |
Inhibitoty effect of Kiom-79, a new herbal prescription, on AGEs formation and expressions of type IV collagen and TGF-β1 in STZ-induced diabetic Rats. |
2006 |
Effect of magnolol(5,5-diallyl-2,2-dihydroxybiphenyl)on diabetic nephropathy in type 2 diabetic Goto-kakizaki rats |
2006 |
Effects of KIOM-79 on hyperglycemia and diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats |
2006 |
Inhibitory Effect of KIOM-79, a New Herbal Prescription, on AGEs Formation and Expressions of Type IV collagen and TGF-β1 in STZ-induced Diabetic Rats |
2005 |
Effect of Traditional Herbal Medicine on the Formation of Advanced Glycation Endproducts (AGEs) in Vitro |