2023-02-23

KIOM researcher selected to lead WHO research project - Systematic map of reviews in traditional medicine to be developed based on global research cooperation □ The Korea Institute of Oriental Medicine (KIOM / President: Lee Jin-Yong) announced that Principal Researcher Lee Myeong-su at its KM Science Research Division had been selected to carry out a research project ordered by the Evidence to Policy and Impact Team of the World Health Organization (WHO). ○ WHO established strategic goals regarding topics drawing increasing global attention and demand in consideration of five key areas (partnership, evidence, data, diversity, and innovation) and is engaged in development and support to help traditional medicine contribute to human-centered global health. □ KIOM cooperated with the National Research Center in Complementary and Alternative Medicine (NAFKAM) in Norway, one of WHO collaborating centers, and was successfully selected after intense competition among organizations in various countries. □ Under KIOM’s leadership, the research team will form a consortium with 10 domestic institutions (including six Korean medicine colleges) and researchers from 19 universities in 10 overseas countries (such as Harvard University in the U.S., Oxford University in the U.K., Beijing University of Chinese Medicine in China, etc.) in implementing the research on “systematic map of reviews on traditional medicine and health outcomes.” □ Systematic literature revi

2022-12-20

KIOM verified improvement of cognitive impairment by Yuk-Gunja-Tang - Newly found efficacy of Yuk-Gunja-Tang expected to lead to development of KM-based anti-dementia drug □ The research team led by Dr. Go Younghoon (first author: Dr. Pak Malk Eun) at the KM Application Center of the Korea Institute of Oriental Medicine (KIOM / President: Lee Jin-Yong) has verified the neuro protection effect of Yuk-Gunja-Tang and proposed the possibility of its usage as an anti-dementia drug. ◦ The outcome of the research was published in international academic journal Frontiers in Pharmacology (IF 5.98; upper 20 percent of JCR) on October 26, 2022. ※ Paper title:　Yuk-Gunja-Tang Attenuates Neuronal Death and Memory　Impairment via ERK/CREB/BDNF Signaling in the Hippocampi of　Experimental Alzheimer’s Disease Model □ Yuk-Gunja-Tang is a herbal formula prepared using ginseng, Atractylodes macrocephala Koidz, Pinellia ternata (Thunb.) Makino, etc., and is known to treat such conditions as functional dyspepsia. □ The research used Yuk-Gunja-Tang approved by the National Institute of Food and Drug Safety Evaluation to implement cellular and animal experiments and discovered its new efficacies including improvement in cognitive behaviors, protection from neuronal cell damage, and activation of growth factors for neuronal cells. ◦Yuk-Gunja-Tang’s effects of cell protection, prevention of mitochondrial dysfunction and oxidative stress reduction were confirmed in hippocampal cells

2022-12-13

KIOM verified anti-influenza virus effect of an ingredient derived from lotus leaf - Expected to be utilized in developing an antiviral agent to protect against new and variant influenza viruses □ The Korea Institute of Oriental Medicine (KIOM / President: Lee Jin-Yong) announced that the research team led by Dr. Ma Jin Yeul (first author: Dr. Cho Won-Kyung) at its KM Application Center had verified strong suppressive effect of an ingredient derived from lotus leaf on influenza viruses. ◦The outcome of the research was published in the October issue of International Journal of Molecular Sciences (IF 6.208), a leading international academic journal. ※ Paper title: Antiviral Effect of Isoquercitrin against Influenza A Viral Infection via Modulating Hemagglutinin and Neuraminidase □ In a previous study, the research team confirmed antiviral effect of lotus leaf extract in suppressing neuraminidase and hemagglutinin, proteins essential for infection and proliferation of influenza viruses. ※ Neuraminidase (NA) is a protein required when influenza viruses replicate and proliferate within cells after initial infection, break out of the cells and spread to neighboring cells. ※ Hemagglutinin (HA) is a protein essential for influenza viruses to attach to and penetrate cells in the early stage of infection. ◦The result of the previous study was published in the Journal of Functional Foods, a leading international academic journal, in March 2022, and a relevant patent applicat