2025 |
Bauhinia coccinea extract prevents scopolamine-induced 2 memory loss through activation of anti-apoptotic and 3 antioxidant pathways in mice |
2024 |
Single acute and repeated subacute toxicity evaluations of Annona atemoya leaf extract with in vitro anti-inflammatory potential |
2024 |
Neuroprotective effects of Elaeagnus glabra f. oxyphylla extract in amyloid-beta-induced cognitive deficit mice: Involvement of the PKC-delta, MYL2, and FER pathways |
2024 |
Non-clinical safety assessment of Annona atemoya leaf extract : evaluation of genotoxicity |
2024 |
Single Oral Toxicity Assessment and Phytochemical Analysis of the Ficus erecta Thunb. Leaf Extract |
2024 |
Neurodegenerative Pathways and Metabolic Changes in the Hippocampus and Cortex of Mice Exposed to Urban Particulate Matter: Insights from an Integrated Interactome Analysis |
2024 |
Therapeutic Potential of Combined Herbal Medicine and Electroacupuncture in Mild Cognitive Impairment through Cytokine Modulation :An observational study |
2024 |
Exploring the therapeutic potential of Potentilla fragarioides var. major (Rosaceae) extract in Alzheimer’s disease using in vitro and in vivo models: a multi-faceted approach |
2023 |
Anti-inflammatory and anti-allergic effects of Cheonwangbosim-dan water extract: An in vitro and in vivo study |
2022 |
Ethanol extract of Elaeagnus glabra f. oxyphylla branches alleviates the inflammatory response through the suppression of cyclin D3/CDK11p58 coupling in lipopolysaccharide-activated BV-2 microglia |
2021 |
Simultaneous quantification of four marker compounds in Bauhinia coccinea extract and their potential inhibitory effects on Alzheimer’s disease biomarkers |
2021 |
Ficus erecta Thunb leaves alleviates memory loss induced by scopolamine in mice via regulation of oxidative stress and cholinergic system. |
2021 |
Korean traditional herbal formula Soshiho-tang attenuates memory impairment and neuronal damage in mice with amyloid-beta-induced Alzheimer’s disease |
2021 |
Ficus erecta Thunb. leaves protect against cognitive deficit and neuronal damage in a mouse model of amyloid-β-induced Alzheimer’s disease. |
2020 |
Similarity of therapeutic networks induced by a multi-component herbal remedy, Ukgansan, in neurovascular unit cells |
2020 |
The Effects of Crinum asiaticum var. japonicum Baker Seeds on Neuroprotection and Antineuroinflammation in Neuronal Cell Lines |
2020 |
Catechol-type flavonoids from the branches of Elaeagnus glabra f. oxyphylla exert the inhibitory effect on amyloid-β aggregation and antioxidant activity |
2019 |
Elaeagnus glabra f. oxyphylla Attenuates Scopolamine-Induced Learning and Memory Impairments in Mice by Improving Cholinergic Transmission via Activation of CREB/NGF Signaling |
2019 |
Annona atemoya Leaf Extract Improves Scopolamine-Induced Memory Impairment by Preventing Hippocampal Cholinergic Dysfunction and Neuronal Cell Death |
2019 |
Annona atemoya leaf extract ameliorates cognitive impairment in amyloid-b injected Alzheimer’s disease-like mouse model |
2019 |
Hwangryunhaedok-Tang Exerts Neuropreventive Effect on Memory Impairment by Reducing Cholinergic System Dysfunction and Inflammatory Response in a Vascular Dementia Rat Model |
2018 |
Tetragonia tetragonioides (Pall.) Kuntze Regulates Androgen Production in a Letrozole-Induced Polycystic Ovary Syndrome Model |
2018 |
Simultaneous Determination of the Traditional Herbal Formula Ukgansan and the In Vitro Antioxidant Activity of Ferulic Acid as an Active Compound |
2018 |
Osteomeles schwerinae extract prevents diabetes-induced renal injury in Spontaneously Diabetic Torii rats |
2018 |
Bojungikgi-Tang, a Traditional Herbal Formula, Exerts Neuroprotective Effects and Ameliorates Memory Impairments in Alzheimer’s Disease-Like Experimental Models |
2016 |
Esculetin, a Coumarin Derivative, Inhibits Aldose Reductase Activity in vitro and Cataractogenesis in Galactose-Fed Rats. |
2016 |
Extract of Polygonum cuspidatum Attenuates Diabetic Retinopathy by Inhibiting the High-Mobility Group Box-1 (HMGB1) Signaling Pathway in Streptozotocin-Induced Diabetic Rats. |
2016 |
Cytoplasmic translocation of high-mobility group box-1 protein is induced by diabetes and high glucose in retinal pericytes |
2016 |
Cnidium officinale extract and butylidenephthalide inhibits retinal neovascularization in vitro and in vivo |
2015 |
Vaccinium myrtillus extract prevents or delays the onset of diabetes–induced blood–retinal barrier breakdown |
2015 |
OSSC1E-K19, a novel phytochemical component of Osteomeles schwerinae, prevents glycated albumin-induced retinal vascular injury in rats. |
2015 |
Anti-glycation and anti-angiogenic activities of 5'-methoxybiphenyl-3,4,3'-triol, a novel phytochemical component of Osteomeles schwerinae |
2015 |
Inhibitory effect of Samul-tang on retinal neovascularization in oxygen-induced retinopathy |
2015 |
Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin‑induced diabetic rats and its active compound emodin inhibits methylglyoxal‑mediated glycation of proteins |
2015 |
Effect of Guibi-Tang, a Traditional Herbal Formula, on Retinal Neovascularization in a Mouse Model of Proliferative Retinopathy |
2015 |
Litsea japonica extract inhibits neuronal apoptosis and the accumulation of advanced glycation end products in the diabetic mouse retina |
2015 |
Litsea japonica Extract Inhibits Aldose Reductase Activity and Hyperglycemia-Induced Lenticular Sorbitol Accumulation in db/db Mice. |
2014 |
Expression of heat shock protein 90 in the kidneys of diabetic db/db mice |
2014 |
Aminoguanidine Protects against Apoptosis of Retinal Ganglion Cells in Zucker Diabetic Fatty Rats |
2014 |
Sipjeondaebo-tang inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy |
2014 |
Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats |
2014 |
HL-217, a new topical anti-angiogenic agent, inhibits retinal vascular leakage and pathogenic subretinal neovascularization in Vldlr−/− mice |
2014 |
Extract of Cassiae semen attenuates diabetic nephropathy via inhibition of advanced glycation end products accumulation in streptozotocin-induced diabetic rats |
2013 |
Effect of KIOM-79 on diabetes-induced myocardial fibrosis in Zucker Diabetic Fatty Rats. |
2013 |
Extract of Litsea japonica ameliorates blood-retinal barrier breakdown in db/db mice. |
2013 |
Ethyl Pyruvate Prevents Methyglyoxal-Induced Retinal Vascular Injury in Rats |
2013 |
Ethyl pyruvate inhibits retinal pathogenic neovascularization by downregulating HMGB-1 expression |
2013 |
The Extract of Litsea japonica Reduced the Development of Diabetic Nephropathy via the Inhibition of Advanced Glycation End Products Accumulation in db/db Mice |
2013 |
Scopoletin Inhibits Rat Aldose Reductase Activity and Cataractogenesis in Galactose-Fed Rats |
2012 |
Renal Podocyte Injury in a RatModel of Type 2 Diabetes Is Prevented byMetformin |
2012 |
Glycoxidised LDL induced the upregulation of Axlreceptor tyrosine kinase and its ligand in mouse mesangial cells |
2012 |
Inhibitory Activities of Cudrania tricuspidata Leaves on Pancreatic Lipase in vitro and Lipolysis in vivo |
2012 |
Puerarin inhibits the retinal pericyte apoptosis induced by advanced glycation end products in vitro and in vivo by inhibiting NADPH oxidase-related oxidative stress. |
2012 |
KIOM-79 Protects AGE-Induced Retinal Pericyte Apoptosis via Inhibition of NF-kappaB Activation In Vitro and In Vivo |
2011 |
Inhibitory Effects of Chlorogenic Acid on Aldose Reductase Activity In Vitro and Cataractogenesis in Galactose-fed Rats |
2011 |
KIOM-79 inhibits aldose reductase acrivity and cataractogenesis in Zucker diabetic fatty rats |
2011 |
Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo. |
2011 |
Elevated N(epsilon)-(carboxymethyl)lysine are associated with apoptosis of retinal pericytes in streptozotocin-induced diabetic rats |
2011 |
Combination of Medicinal Herbs KIOM-79 Reduces Advanced Glycation End Product Accumulation and the Expression of Inflammatory Fzceors in the Aorta of Zucker Diabetic Fatty Rats |
2011 |
The role of high-mobility group box-1 protein in the development of diabetic nephropathy |
2010 |
Involvement of advanced glycation end products, oxidative stress and nuclear factor-kappaB in the development of diabetic keratopathy. |
2010 |
Anti-lipase and Lipolytic Activities of EtOH Extract from Juniperus rigida |
2010 |
Lens epithelial cell apoptosis initiates diabetic cataractogenesis in the Zucker diabetic fatty rat. |
2010 |
KIOM-79 Prevents Lens Epithelial Cell Apoptosis and Lens Opacification in Zucker Diabetic Fatty Rats. |
2010 |
Renal Podocyte Apoptosis in Zucker Diabetic Fatty Rats: Involvement of Methylglyoxal-Induced Oxidative DNA Damage. |
2010 |
Protection against advanced glycation end products and oxidative stress during the development of diabetic keratopathy by KIOM-79 |
2009 |
Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells |
2009 |
Extract of the aerial parts of Aster koraiensis reduced development of diabetic nephropathy via anti-apoptosis of podocytes in streptozotocin-induced diabetic rats. |
2009 |
KIOM-79, an Inhibitor of AGEs–Protein Cross-linking, Prevents Progression of Nephropathy in Zucker Diabetic Fatty Rats |
2008 |
스트렙토조토신으로 유도된 당뇨백서의 망막과 혈청에서 혈관내피세포 성장인자와 최종당화산물의 과발현 및 수정체 혼탁 |
2008 |
KIOM-79 prevents apoptotic cell death and AGEs accumulation in retinas of diabetic db/db mice |
2007 |
Effects of magnolol (5,5'-diallyl-'2,2'-dihydroxybiphenyl) on diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats |
2007 |
Methanol Extract of Sorbus Commixta Cortex Prevents Vascular Inflammation in Rats with a High Fructose-Induced Metabolic Syndrome |
2007 |
Effects of KIOM-79 on hyperglycemia and diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats |
2006 |
Inhibitory Effect of KIOM-79, a New Herbal Prescription, on AGEs Formation and Expressions of Type IV collagen and TGF-β1 in STZ-induced Diabetic Rats |
2006 |
The positive inotropic effect of the aqueous extract of Convallaria keiskei in beating rabbit atria |
2006 |
복합한약제제 KIOM-79의 STZ 유도 당뇨 모델에서의 최종당화산물 생성 및 Type IV Collagen 및 TGF-β1의 발현억제 효과 |
2006 |
Effect of magnolol(5,5-diallyl-2,2-dihydroxybiphenyl)on diabetic nephropathy in type 2 diabetic Goto-kakizaki rats |
2006 |
선학초 부탄올 추출물의 혈관 이완 효과의 기전에 대한 연구 |
2006 |
Effects of KIOM-79 on hyperglycemia and diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats |
2006 |
Anti-atherosclerotic effect of the Methanol extract of Sorbus commixta cortex in the High cholesterol-diet rats |
2006 |
Yukmijiwang-tang ameliorates ischemia/reperfusion-induced renal ihjury in rats |
2006 |
Antihypertensive effects of the Methanol extract of Sorbus Cortex in the Nitric Oxide-deficient hypertensive rat |
2006 |
Mechanism for the Vascular Relaxation Induced by Butanol Extract of Agrimonia pilosa |
2006 |
Inhibitoty effect of Kiom-79, a new herbal prescription, on AGEs formation and expressions of type IV collagen and TGF-β1 in STZ-induced diabetic Rats. |
2005 |
Effect of Traditional Herbal Medicine on the Formation of Advanced Glycation Endproducts (AGEs) in Vitro |
2005 |
Anti-atherogenic effects of the methanol extract of Sorbus cortex in atherogenic-diet rats. |
2005 |
Effect of methanol Extract of Sorbus Cortex in a Rat Model of L-NAME-induced Atherosclerosis |