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김찬식 노화유발 쥐에서 고지방식이가 신장손상에 미치는 영향과 운동 및 홍삼에 의한 신장손상 개선 효능 연구

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2023 Isobavachin from Psoralea corylifolia alleviates lipopolysaccharide-induced inflammatory responses in macrophages and zebrafish by suppressing the MAPK and NF-κB signaling pathways
2023 Gene expression profiling of nasal inflammatory dysfunctions induced by diesel particles using an in vivo system
2022 Particulate matter exposure and the changes in immune bi-omarkers: Effects of Biyeom-go on the nasal mucosa of patients with allergic rhinitis and a particulate matter-treated mouse model
2021 Evaluation of oral toxicity and genotoxicity of Achyranthis Radix extract
2021 Extract of Moutan radicis cortex and Cinnamomi ramulus ameliorates laser-induced choroidal neovascularization in Brown-Norway rats
2021 Damage to Olfactory Organs of Adult Zebrafish Induced by Diesel Particulate Matter
2020 The herbal combination CPA4-1 inhibits changes in retinal capillaries and reduction of retinal occludin in db/db mice
2020 Toxicological effects of urban particulate matter on corneal and conjunctival epithelial cells
2020 New application for assessment of dry eye syndrome induced by particulate matter exposure
2020 Anti-inflammatory isocoumarins from the bark of Fraxinus chinensis subsp. rhynchophylla
2020 POCU1b, the n-Butanol Soluble Fraction of Polygoni Cuspidati Rhizoma et Radix, Attenuates Obesity, Non-Alcoholic Fatty Liver and Insulin Resistance via Inhibitions of Pancreatic Lipase and cAMP-dependent PDE activity, AMPK activation and SOCS-3 suppression
2020 Achyranthis Radix extract loaded eye drop formulation development and novel evaluation method for dry eye treatment
2020 Method for the Rapid Screening of Drug Candidates Using Single‐Protein Tracking in a Living Cell
2020 Anti-angiogenic effect of EGHB010, a standardized herbal formula of Paeoniae radix and Glycyrrhizae radix
2019 Polydatin inhibits NLRP3 inflammasome in dry eye disease by attenuating oxidative stress and inhibiting the NF-κB pathway
2019 Topical Application of Liriope platyphylla Extract Attenuates Dry Eye Syndrome Induced by Particulate Matter
2019 Apricot Kernel Extract and Amygdalin Inhibit Urban Particulate Matter-Induced Keratoconjunctivitis Sicca
2019 Polygonum cuspidatum stem extract (PSE) attenuates dry eye disease by inhibiting inflammation and apoptosis
2019 Improvement in diabetic retinopathy through protection against retinal apoptosis in spontaneously diabetic Torii rats mediated by ethanol extract of Osteomeles schwerinae C.K. Schneid.
2019 Pueraria lobata extract protects hydrogen peroxide-induced human retinal pigment epithelial cells death and membrane permeability
2019 Achyranthis radix Extract Improves Urban Particulate Matter-Induced Dry Eye Disease
2018 Aster koraiensis extract improves impaired skin wound healing during hyperglycemia
2018 Aster koraiensis extract lowers postprandial glucose in normoglycemic and high-fat-diet-induced obese mice
2018 The protective effect of Polygonum cuspidatum (PCE) aqueous extract in a dry eye
2018 Antioxidant and α-Glucosidase Inhibitory Activities of the Extracts of Aster koraiensis Leaves
2018 Osteomeles schwerinae extract prevents diabetes-induced renal injury in Spontaneously Diabetic Torii rats
2018 Aster Koraiensis extract and chlorogenic acid inhibit retinal angiogenesis in a mouse model of oxygen-induced retinopathy
2018 Identification and Quantification of Human Neutrophil Elastase Inhibitory Caffeoylquinic Acids in the Leaves of Aster koraiensis
2018 홍삼가수분해추출물의 db/db 마우스에서 신장 손상 예방효과
2017 GS-E3D, a new pectin lyase-modified red ginseng extract, inhibited diabetes-related renal dysfunction in streptozotocin-induced diabetic rats
2017 EGHB010, a Standardized Extract of Paeoniae Radix and Glycyrrhizae Radix, Inhibits VEGF-Induced Tube Formation In Vitro and Retinal Vascular Leakage and Choroidal Neovascularization In Vivo
2017 Aster koraiensis extract prevents diabetes-induced retinal vascular dysfunction in spontaneously diabetic Torii rats
2017 Phenolic Compounds from the Leaves of Homonoia riparia and their Inhibitory Effects on Advanced Glycation End Product Formation
2017 The role of glycation in the pathogenesis of aging and its prevention through herbal products and physical exercise
2017 Pectin lyase-modified red ginseng extract exhibits potent anti-glycation effects in vitro and in vivo
2016 Topical Application of Apricot Kernel Extract Improves Dry Eye Symptoms in a Unilateral Exorbital Lacrimal Gland Excision Mouse
2016 Esculetin, a Coumarin Derivative, Inhibits Aldose Reductase Activity in vitro and Cataractogenesis in Galactose-Fed Rats.
2016 Jakyakgamcho-tang and its major component, Paeonia lactiflora, exhibit potent anti-glycation properties
2016 Extract of Polygonum cuspidatum Attenuates Diabetic Retinopathy by Inhibiting the High-Mobility Group Box-1 (HMGB1) Signaling Pathway in Streptozotocin-Induced Diabetic Rats.
2016 벌개미취 에탄올추출물의 STZ-유도 당뇨 모델에서의 최종당화산물의 생성 및 교차결합에 미치는 효과
2016 The Extract of Aster Koraiensis Prevents Retinal Pericyte Apoptosis in Diabetic Rats and Its Active Compound, Chlorogenic Acid Inhibits AGE Formation and AGE/RAGE Interaction
2016 Cytoplasmic translocation of high-mobility group box-1 protein is induced by diabetes and high glucose in retinal pericytes
2016 Cnidium officinale extract and butylidenephthalide inhibits retinal neovascularization in vitro and in vivo
2015 Epicatechin breaks preformed glycated serum albumin and reverses the retina laccumulation ofadvanced glycation end products
2015 Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin‑induced diabetic rats and its active compound emodin inhibits methylglyoxal‑mediated glycation of proteins
2015 Litsea japonica extract inhibits neuronal apoptosis and the accumulation of advanced glycation end products in the diabetic mouse retina
2015 Effect of Guibi-Tang, a Traditional Herbal Formula, on Retinal Neovascularization in a Mouse Model of Proliferative Retinopathy
2015 Myricetin inhibits advanced glycation end product (AGE)-induced migration of retinal pericytes through phosphorylation of ERK1/2, FAK-1, and paxillin in vitro and in vivo
2015 Vaccinium myrtillus extract prevents or delays the onset of diabetes–induced blood–retinal barrier breakdown
2015 Treadmill Exercise Attenuates Retinal Oxidative Stress in Naturally-Aged Mice: An Immunohistochemical Study
2015 Anti-glycation and anti-angiogenic activities of 5'-methoxybiphenyl-3,4,3'-triol, a novel phytochemical component of Osteomeles schwerinae
2015 Gemigliptin, a dipeptidyl peptidase-4 inhibitor, inhibits retinal pericyte injury in db/db mice and retinal neovascularization in mice with ischemic retinopathy.
2015 Inhibitory effect of Samul-tang on retinal neovascularization in oxygen-induced retinopathy
2015 Litsea japonica Extract Inhibits Aldose Reductase Activity and Hyperglycemia-Induced Lenticular Sorbitol Accumulation in db/db Mice.
2015 OSSC1E-K19, a novel phytochemical component of Osteomeles schwerinae, prevents glycated albumin-induced retinal vascular injury in rats.
2014 Sipjeondaebo-tang inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy
2014 Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats
2014 HL-217, a new topical anti-angiogenic agent, inhibits retinal vascular leakage and pathogenic subretinal neovascularization in Vldlr−/− mice
2014 Extract of Cassiae semen attenuates diabetic nephropathy via inhibition of advanced glycation end products accumulation in streptozotocin-induced diabetic rats
2014 Aminoguanidine Protects against Apoptosis of Retinal Ganglion Cells in Zucker Diabetic Fatty Rats
2014 A high-fat diet increases oxidative renal injury and protein glycation in D-galactose-induced aging rats and its prevention by Korea red ginseng
2014 Expression of heat shock protein 90 in the kidneys of diabetic db/db mice
2013 Extract of Litsea japonica ameliorates blood-retinal barrier breakdown in db/db mice.
2013 Ethyl Pyruvate Prevents Methyglyoxal-Induced Retinal Vascular Injury in Rats
2013 Effect of regular exercise on the histochemical changes of ᴅ-galactose-induced oxidative renal injury in high-fat diet-fed rats
2013 The Extract of Litsea japonica Reduced the Development of Diabetic Nephropathy via the Inhibition of Advanced Glycation End Products Accumulation in db/db Mice
2013 Ethyl pyruvate inhibits retinal pathogenic neovascularization by downregulating HMGB-1 expression
2013 Scopoletin Inhibits Rat Aldose Reductase Activity and Cataractogenesis in Galactose-Fed Rats
2013 Effect of KIOM-79 on diabetes-induced myocardial fibrosis in Zucker Diabetic Fatty Rats.
2012 Inhibitory Activities of Cudrania tricuspidata Leaves on Pancreatic Lipase in vitro and Lipolysis in vivo
2012 Cycloartane-Type Triterpenes from the Leaves of Homonoia riparia with VEGF-Induced Angiogenesis Inhibitory Activity
2012 Puerarin inhibits the retinal pericyte apoptosis induced by advanced glycation end products in vitro and in vivo by inhibiting NADPH oxidase-related oxidative stress.
2012 KIOM-79 Protects AGE-Induced Retinal Pericyte Apoptosis via Inhibition of NF-kappaB Activation In Vitro and In Vivo
2012 Renal Podocyte Injury in a RatModel of Type 2 Diabetes Is Prevented byMetformin
2012 Methylglyoxal induces hyperpermeability of the blood-retinal barrier via the loss of tight junction proteins and the activation of matrix metalloproteinases.
2011 Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo.
2011 The role of high-mobility group box-1 protein in the development of diabetic nephropathy
2011 Inhibitory Effects of Chlorogenic Acid on Aldose Reductase Activity In Vitro and Cataractogenesis in Galactose-fed Rats
2011 KIOM-79 inhibits aldose reductase acrivity and cataractogenesis in Zucker diabetic fatty rats
2011 Elevated N(epsilon)-(carboxymethyl)lysine are associated with apoptosis of retinal pericytes in streptozotocin-induced diabetic rats
2011 Betulinic Acid has an Inhibitory Effect on Pancreatic Lipase and Induces Adipocyte Lipolysis
2011 Chlorogenic acid inhibits the formation of advanced glycation end products and associated protein cross-linking.
2011 Combination of Medicinal Herbs KIOM-79 Reduces Advanced Glycation End Product Accumulation and the Expression of Inflammatory Fzceors in the Aorta of Zucker Diabetic Fatty Rats
2010 Protection against advanced glycation end products and oxidative stress during the development of diabetic keratopathy by KIOM-79
2010 KIOM-79 prevents methyglyoxal-induced retinal pericyte apoptosis in vitro and in vivo.
2010 Involvement of advanced glycation end products, oxidative stress and nuclear factor-kappaB in the development of diabetic keratopathy.
2010 Lens epithelial cell apoptosis initiates diabetic cataractogenesis in the Zucker diabetic fatty rat.
2010 Anti-lipase and Lipolytic Activities of EtOH Extract from Juniperus rigida
2010 KIOM-79 Prevents Lens Epithelial Cell Apoptosis and Lens Opacification in Zucker Diabetic Fatty Rats.
2010 Renal Podocyte Apoptosis in Zucker Diabetic Fatty Rats: Involvement of Methylglyoxal-Induced Oxidative DNA Damage.
2010 Cytotoxic role of methylglyoxal in rat retinal pericytes: Involvement of a nuclear factor-kappaB and inducible nitric oxide synthase pathway.
2009 KIOM-79, an Inhibitor of AGEs–Protein Cross-linking, Prevents Progression of Nephropathy in Zucker Diabetic Fatty Rats
2009 Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells
2009 3,5-Di-O-caffeoyl-epi-quinic Acid from the Leaves and Stems of Erigeron annuus Inhibits Protein Glycation, Aldose Reductase, and Cataractogenesis.
2009 Extract of the aerial parts of Aster koraiensis reduced development of diabetic nephropathy via anti-apoptosis of podocytes in streptozotocin-induced diabetic rats.
2009 알도즈 환원효소 활성억제와 소비톨 축적 억제로 인한 벌개미취 추출물의 당뇨병성 백내장 발병 지연 효능
2009 Novel application of surface plasmon resonance biosensor chips for measurementof advanced glycation end products in serum of Zucker diabetic fatty rats.
2008 스트렙토조토신으로 유도된 당뇨백서의 망막과 혈청에서 혈관내피세포 성장인자와 최종당화산물의 과발현 및 수정체 혼탁
2008 KIOM-79 prevents apoptotic cell death and AGEs accumulation in retinas of diabetic db/db mice
2008 Flavan-3-ols from Ulmus davidiana var. japonica with Inhibitory Activity on Protein Glycation
2008 산수유씨의 최종당화산물의 형성 및 교차결합에 미치는 효과
2007 Effects of magnolol (5,5'-diallyl-'2,2'-dihydroxybiphenyl) on diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats
2007 Anthraquinones from the seeds of Cassia tora with inhibitory activity on protein glycation and aldose reductase
2007 Effects of KIOM-79 on hyperglycemia and diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats
2006 Inhibitoty effect of Kiom-79, a new herbal prescription, on AGEs formation and expressions of type IV collagen and TGF-β1 in STZ-induced diabetic Rats.
2006 Effect of magnolol(5,5-diallyl-2,2-dihydroxybiphenyl)on diabetic nephropathy in type 2 diabetic Goto-kakizaki rats
2006 Effects of KIOM-79 on hyperglycemia and diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats
2006 Inhibitory Effect of KIOM-79, a New Herbal Prescription, on AGEs Formation and Expressions of Type IV collagen and TGF-β1 in STZ-induced Diabetic Rats
2006 복합한약제제 KIOM-79의 STZ 유도 당뇨 모델에서의 최종당화산물 생성 및 Type IV Collagen 및 TGF-β1의 발현억제 효과
2005 Effect of Traditional Herbal Medicine on the Formation of Advanced Glycation Endproducts (AGEs) in Vitro

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